(C) E. A. Katrukha, M. Mikhaylova, H. X. van Brakel, P. M. van Bergen en Henegouwen, A. Akhmanova, C. C. Hoogenraad, L. C. Kapitein "Probing cytoskeletal modulation of passive and active intracellular dynamics using nanobody-functionalized quantum dots" BioRxiv preprint first posted online Nov. 23, 2016; doi: http://dx.doi.org/10.1101/089284 (accepted to Nature Communications). DISCLAIMER: These data have been kindly provided by L.C.Kapitein/E.A.Katrukha and posted onto the INADILIC website according to the authors' permission (30/12/2016). These data can be freely used for testing statistical methods and biophysical models under the condition of providing the appropriate credits to the authors and citing the above preprint which presents and describes the data. The acknowledgment to the INADILIC website is also welcome. Two-dimensional trajectories of quantum dots (QDs) with a measured Stokes radius of 14.4 nm inside cells under different conditions (see further details in the paper). There are 6 groups of trajectories (in 6 folders): 1) QD_control (control group): 485 trajectories 2) QD_wLatrunculinA (inside cells with actin depolymerized using LatrunculinA) 435 trajectories 3) Kinesin1_QD (QDs attached to kinesin-1 motor proteins) 91 trajectories 4) Kinesin2_QD (QDs attached to kinesin-2 motor proteins) 134 trajectories 5) Kinesin3_QD (QDs attached to kinesin-3 motor proteins) 181 trajectories 6) Kinesin4_QD (QDs attached to kinesin-4 motor proteins) 26 trajectories Each file (ASCII text format) contains one trajectory and has 3 columns: the time stamp (in seconds), the X coordinate (in micrometers), and the Y coordinate (in micrometers), with the time step of 2.4 ms (1-2) and 50 ms (3-6). Note that duration of trajectories can vary significantly, from few tens to two thousand points and initial time moment for each trajectory can be different from zero. These data can be loaded in Matlab by 'importdata' command (see also function 'A_Katrukha_load.m')